Name :
Human NPR1 Protein, hFc Tag
Uniprot ID :
P16066
Common Name :
Synonyms :
ANP-A;ANPR-A;ANPRA;NPR-A;GC-A
Application :
Recommended Dilutions :
Formulation &Reconstitution :
Lyophilized from sterile PBS, pH 7.4. Normally 5 % – 8% trehalose is added as protectants before lyophilization. Please see Certificate of Analysis for specific instructions of reconstitution.
Host Species :
IgG type :
Reactivity :
Target :
NPR1
Description :
Recombinant human NPR1 protein with C-terminal human Fc tag
Delivery :
In Stock
Storage&Shipping :
Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
Background :
Guanylyl cyclases, catalyzing the production of cGMP from GTP, are classified as soluble and membrane forms (Garbers and Lowe, 1994 [PubMed 7982997]). The membrane guanylyl cyclases, often termed guanylyl cyclases A through F, form a family of cell-surface receptors with a similar topographic structure: an extracellular ligand-binding domain, a single membrane-spanning domain, and an intracellular region that contains a protein kinase-like domain and a cyclase catalytic domain. GC-A and GC-B function as receptors for natriuretic peptides; they are also referred to as atrial natriuretic peptide receptor A (NPR1) and type B (NPR2; MIM 108961). Also see NPR3 (MIM 108962), which encodes a protein with only the ligand-binding transmembrane and 37-amino acid cytoplasmic domains. NPR1 is a membrane-bound guanylate cyclase that serves as the receptor for both atrial and brain natriuretic peptides (ANP (MIM 108780) and BNP (MIM 600295), respectively).[supplied by OMIM, May 2009]
Usage :
Research use only
Related websites: https://www.medchemexpress.com/antibodies.html
Popular product recommendations:
Notch 1 Antibody
beta Tubulin Antibody
FGFR2 Antibody: FGFR2 Antibody is a non-conjugated and Rabbit origined monoclonal antibody about 92 kDa, targeting to FGFR2. It can be used for WB,IP assays with tag free, in the background of Human.