Thu. Jul 18th, 2024

Name :
Anti-CD44 antibody(DMC269); IgG1 Chimeric mAb

Uniprot ID :
P16070

Common Name :

Synonyms :
CD44;CDW44;CSPG8;ECMR-III;HCELL;HUTCH-I;IN;LHR;MC56;MDU2;MDU3;MIC4;Pgp1;Epican

Application :
Flow Cyt

Recommended Dilutions :
Flow Cyt 1:100

Formulation &Reconstitution :
Lyophilized from sterile PBS, pH 7.4. Normally 5 % – 8% trehalose is added as protectants before lyophilization. Please see Certificate of Analysis for specific instructions of reconstitution.

Host Species :
Rabbit

IgG type :
Rabbit/Human Fc chimeric IgG1

Reactivity :
Human

Target :
CD44

Description :
Anti-CD44 antibody(DMC269); IgG1 Chimeric mAb

Delivery :
In Stock

Storage&Shipping :
Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.

Background :
The protein encoded by this gene is a cell-surface glycoprotein involved in cell-cell interactions; cell adhesion and migration. It is a receptor for hyaluronic acid (HA) and can also interact with other ligands; such as osteopontin; collagens; and matrix metalloproteinases (MMPs). This protein participates in a wide variety of cellular functions including lymphocyte activation; recirculation and homing; hematopoiesis; and tumor metastasis. Transcripts for this gene undergo complex alternative splicing that results in many functionally distinct isoforms; however; the full length nature of some of these variants has not been determined. Alternative splicing is the basis for the structural and functional diversity of this protein; and may be related to tumor metastasis.

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Usage :
Research use only

Antibodies are immunoglobulins secreted by effector lymphoid B cells into the bloodstream. Antibodies consist of two light peptide chains and two heavy peptide chains that are linked to each other by disulfide bonds to form a “Y” shaped structure. Both tips of the “Y” structure contain binding sites for a specific antigen. Antibodies are commonly used in medical research, pharmacological research, laboratory research, and health and epidemiological research. They play an important role in hot research areas such as targeted drug development, in vitro diagnostic assays, characterization of signaling pathways, detection of protein expression levels, and identification of candidate biomarkers.
Related websites: https://www.medchemexpress.com/antibodies.html
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