Tue. May 21st, 2024

Name :
Anti-CD27 antibody(DM59), Rabbit mAb

Uniprot ID :
P26842

Common Name :

Synonyms :
CD27; TNFRSF7; S152; T14; Tp55

Application :
ELISA; Flow Cyt; WB; IHC

Recommended Dilutions :
ELISA 1:5000-10000; Flow Cyt 1:100; WB 1:1000; IHC 1:100

Formulation &Reconstitution :
Lyophilized from sterile PBS, pH 7.4. Normally 5 % – 8% trehalose is added as protectants before lyophilization. Please see Certificate of Analysis for specific instructions of reconstitution.

Host Species :
Rabbit

IgG type :
Rabbit IgG

Reactivity :
Human

Target :
CD27

Description :
Anti-CD27 antibody(DM59); Rabbit mAb

Delivery :
In Stock

Storage&Shipping :
Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.

Background :
The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor is required for generation and long-term maintenance of T cell immunity. It binds to ligand CD70; and plays a key role in regulating B-cell activation and immunoglobulin synthesis. This receptor transduces signals that lead to the activation of NF-kappaB and MAPK8:JNK. Adaptor proteins TRAF2 and TRAF5 have been shown to mediate the signaling process of this receptor. CD27-binding protein (SIVA); a proapoptotic protein; can bind to this receptor and is thought to play an important role in the apoptosis induced by this receptor.

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Usage :
Research use only

Antibodies are immunoglobulins secreted by effector lymphoid B cells into the bloodstream. Antibodies consist of two light peptide chains and two heavy peptide chains that are linked to each other by disulfide bonds to form a “Y” shaped structure. Both tips of the “Y” structure contain binding sites for a specific antigen. Antibodies are commonly used in medical research, pharmacological research, laboratory research, and health and epidemiological research. They play an important role in hot research areas such as targeted drug development, in vitro diagnostic assays, characterization of signaling pathways, detection of protein expression levels, and identification of candidate biomarkers.
Related websites: https://www.medchemexpress.com/antibodies.html
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