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On for postpartum hemorrhageTable 2. Comparison of BDNF, Mouse (R129A, R130A, HEK293, C-His) clinical traits involving PAE group and hysterectomy group Characteristic Maternal traits Age (yr) Primiparity Twin pregnancy Preeclampsia Previous Cesarean delivery Neonatal traits Gestational age (wk) 34 34?6 wk 6 day 37 Birth weight four,000 g Delivery mode Vaginal Cesarean PPH qualities Reason for PPH Uterine atony Abnormal placentation Low genital tract trauma Retained placental fragments Othersc)PAE group (n=117)a) 32.0 ?5.0 56 (47.9) 3 (2.6) 7 (6.0) 24 (20.five)Hysterectomy group (n=20)b) 35.0 ?four.0 four (20.0) 0 (0.0) 3 (15.0) 14 (70.0)P -value0.006 0.027 0.999 0.167 0.001 0.1 (0.9) 12 (ten.three) 104 (88.9) eight (6.8) 69 (59.0) 48 (41.0)1 (five.0) 5 (25.0) 14 (70.0) 0 (0.0) 3 (15.0) 17 (85.0) 0.999 0.64 (54.7) 17 (14.five) 25 (21.4) 3 (two.6) 8 (6.8) 33 (28.4) 90 (76.9) 53 (45.3) 55 (47.0) 43 (36.8)two (ten.0) 15 (75.0) 3 (15.0) 0 (0.0) 0 (0.0) three (15.0) five (25.0) 4 (80.0)a) two (40.0) 19 (95.0)0.001 0.001 0.517 0.999 – 0.131 0.001 0.165 0.573 0.Overt DIC Hospital-to-hospital transfer Peri-interventional characteristics Hemodynamic instability Initial hemoglobin eight g/dL Extra than 10 RBCU transfusedBinary logistic regression analysis was performed. Data are presented as quantity ( ) or mean ?regular deviation. PAE, pelvic arterial embolization; PPH, postpartum hemorrhage; DIC, disseminated intravascular coagulation; RBCU, red blood cell unit. a) Amongst 117 patients, five sufferers underwent hemostatic hysterectomy soon after PAE failure; b)Amongst 20 sufferers, 15 patients mainly underwent Cesarean hysterectomy whereas hemostatic hysterectomy was mostly performed in five patients just after vaginal (three sufferers) or Cesarean (2 individuals) delivery; c)Other folks include things like pseudoaneurysm on the vaginal (1 patient) and superior vesical arteries (1 patient) and also the injury of inferior epigastric (5 individuals) and superior vesical arteries (1 patient).individuals). The good results group showed great clinical outcomes, but 3 cases of uterine necrosis occurred. Fourteen sufferers were clinical failures that required hemostatic hysterectomies (4 instances) and repeat PAE (10 instances). On univariate evaluation, failure of PAE was associated with overt DIC (25 vs. eight individuals, P = 0.009), much more than 10 RBCUs transfused (32 vs.11 sufferers, P = 0.002) and embolization of both uterine and ovarian arteries (4 vs. four sufferers, P = 0.003) (Table 3). Multivariate analysis showed that PAE failure was only associated with extra than 10 RBCUs transfused (odds ratio, eight.011; 95 self-assurance interval, 1.531?1.912; P = 0.014) and embolization of both uterine and ovarian arteries (oddsogscience.orgVol. 57, No. 1,Table 3. Comparison of clinical traits between effective and failed PAE Characteristic Maternal qualities Age (yr) Primiparity Preeclampsia Twin pregnancy Previous Cesarean delivery Neonatal traits Gestational age (wk) 34 34?6 wk six day 37 Birth weight four,000 g Mode of delivery Vaginal Cesarean PPH characteristics Sort of PPH Key Secondary Reason for PPH Uterine atony Abnormal placentation Low genital tract trauma Retained placental fragments VHL Protein Formulation Othersa) Overt DIC Hospital-to-hospital transfer Peri-interventional qualities Hemodynamic instability Initial hemoglobin eight g/dL Much more than ten RBCU transfused Nature of embolizing agent Short-term Permanent Nature of arteries embolized Cervicovaginal branch Uterine artery Internal iliac artery and/or branches Uterine and ovarian arteries Othersb) No. of PAE 1 two PAE results (n=103).