Tue. May 7th, 2024

Alda-1

Alda-1Band: www.medchemexpress.comNovel aldehyde dehydrogenase 2 (ALDH2) agonist  CAS No: 349438-38-6   Chemical Name: Alda 1; N-(1,3-Benzodioxole-5-ylmethyl)-2,6-dichlorobenzamide ABT-199 Molecular Formula C15H11Cl2NO3 Molecular Weight 324.16 CAS Numbers 349438-38-6 Storage Condition 0°C (short term), -20°C…

2-D08

2-D08Band: www.medchemexpress.comPotent sumoylation inhibitor, acting by inhibiting the transfer of SUMO-1 from the E2 thioester to the SUMO substrateChemical Name: 2,3,4-Trihydroxyflavone; 2-(2,3,4-Trihydroxyphenyl)-4H-1-benzopyran-4-one CAS No: 144707-18-6 LMI070 Molecular Formula C15H10O5 Molecular Weight 270.24…

0990CL

0990CLBand: www.medchemexpress.comNovel inhibitor of heterotrimeric Gαi subunits CAS No: 511514-03-7   Chemical Name: (4-Phenyl-quinazolin-2-yl)-(4,6,6-trimethyl-1,6-dihydro-pyrimidin-2-yl)-amine GSK126 Molecular Formula C21H21N5 Molecular Weight 343.42 CAS Numbers 511514-03-7 Storage Condition 0°C (short term), -20°C…

pythiDC

pythiDCBand: www.medchemexpress.comNovel selective inhibitor of collagen prolyl 4-hydroxylase, neither causing general toxicity nor disrupting iron homeostasis   RG7388 Molecular Formula C10H6N2O4S Molecular Weight 250.23 CAS Numbers 1821370-71-1 Storage Condition 0°C…

NSC-632839

NSC-632839Band: www.medchemexpress.comInhibitor of the ubiquitin isopeptidases, inducing a rather unique apoptotic pathway including a Bcl-2-dependent but apoptosome-independent mitochondrial pathway with up-regulation of the BH3-only protein Noxa CAS No: 157654-67-6   Chemical…

BMS-8

BMS-8Band: www.medchemexpress.comNovel inhibitor of the PD-1/PD-L1 interaction by inducing PD-L1 dimerization through PD-1 interacting surface, binding at a hydrophobic cavity formed upon PD-L1 dimerization CAS No: 1675201-90-7   Chemical Name: 1--piperidine-2-carboxylic acid…

BMS-202

BMS-202Band: www.medchemexpress.comNovel inhibitor of the PD-1/PD-L1 interaction by inducing PD-L1 dimerization through PD-1 interacting surface CAS No: 1675203-84-5   Chemical Name: N-(2-{-amino}-ethyl)-acetamide TAK-242 Molecular Formula C₂₅H₂₉N₃O₃ Molecular Weight 419.52 CAS Numbers 1675203-84-5…

Shield-1

Shield-1Band: www.medchemexpress.comNovel cell permeable small molecule redulator of specific protein functions The Shield-1 ligand can simultaneously stabilizes and destabilizes a protein of interest depending on the amount of the ligand used within…

SAFit2

SAFit2Band: www.medchemexpress.comHighly selective inhibitor of the ​FK506-binding protein 51 (FKBP51)CAS No: 1643125-33-0   Chemical Name: (S)-((R)-3-(3,4-Dimethoxyphenyl)-1-(3-(2-morpholinoethoxy)phenyl)propyl) 1-((S)-2-cyclohexyl-2-(3,4,5-trimethoxyphenyl)acetyl)piperidine-2-carboxylate LY2835219 Molecular Formula C46H62N2O10 Molecular Weight 802.99 CAS Numbers 1643125-33-0 Storage Condition 0°C (short term),…

SAFit1

SAFit1Band: www.medchemexpress.comHighly selective inhibitor of the ​FK506-binding protein 51 (FKBP51)   Monomethyl auristatin E Molecular Formula C42H53NO11 Molecular Weight 747.87 CAS Numbers 1643125-32-9 Storage Condition 0°C (short term), -20°C (long…