Tue. May 28th, 2024

NSC-632839

Band: www.medchemexpress.com

Inhibitor of the ubiquitin isopeptidases, inducing a rather unique apoptotic pathway including a Bcl-2-dependent but apoptosome-independent mitochondrial pathway with up-regulation of the BH3-only protein Noxa

CAS No: 157654-67-6

 

Chemical Name: F6; 3,5-Bis[(4-methylphenyl)methylene]-4-piperidione hydrochloride

Navitoclax

Molecular Formula C21H21NO • HCl
Molecular Weight 339.9
CAS Numbers 157654-67-6
Storage Condition 0°C (short term), -20°C (long term), desiccated
Solubility DMSO
Purity 98% by HPLC

References PubMed ID::http://www.ncbi.nlm.nih.gov/pubmed/18486607

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