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UNC0379

Band: www.medchemexpress.com

A selective, substrate-competitive inhibitor of the lysine methyltransferase SETD8 with IC50 of 7.3±1.0 uM

Reference:

Ma A, et al. Discovery of a Selective, Substrate-Competitive Inhibitor of the Lysine Methyltransferase SETD8. J Med Chem. 2014 Aug 14;57(15):6822-33.

CAS No: 1620401-82-2

 

Chemical Name: 6,7-Dimethoxy-2-(pyrrolidin-1-yl)-N-(5-(pyrrolidin-1-yl)pentyl)quinazolin-4-amine

AZD2016

Molecular Formula C23H35N5O2
Molecular Weight 413.56
CAS Numbers 1620401-82-2
Storage Condition 0°C (short term), -20°C (long term), desiccated
Solubility more than 25 mg/mL/DMSO
Purity 98% by HPLC

References PubMed ID::http://www.ncbi.nlm.nih.gov/pubmed/18506595

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