Sat. Jul 27th, 2024

PD 158780

Band: www.medchemexpress.com

Potent inhibitor of ErbB receptor family tyrosine kinases (IC50 values are 0.008, 49 and 52 nM for EGFR, ErbB2 and ErbB2/ErbB4 respectively) that does not inhibit FGF or PDGF-mediated tyrosine phosphorylation

CAS No:171179-06-9

Chemical Name: N4-(3-Bromophenyl)-N6-methyl-pyrido[3,4-d]pyrimidine-4,6-diamine

ACY-1220

Molecular Formula C14H12BrN5
Molecular Weight 330.18
CAS Numbers 171179-06-9
Storage Condition 0°C (short term), -20°C (long term), desiccated
Solubility DMSO
Purity 98% by HPLC

References PubMed ID::http://www.ncbi.nlm.nih.gov/pubmed/18535782

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