PD0332991 (Palbociclib) HCl
Band: www.medchemexpress.com
An orally active, selective inhibitor of the cyclin D kinases Cdk4 (IC50 = 11 nM) and Cdk6 (IC50= 16 nM) with no activity against a panel of 36 additional protein kinases
CAS No:827022-32-2
Chemical Name: 6-acetyl-8-cyclopentyl-5-methyl-2-[[5-(1-piperazinyl)-2-pyridinyl]amino]-pyrido[2,3-d]pyrimidin-7(8H)-one, monohydrochloride
| Molecular Formula | C24H29N7O2 • HCl |
| Molecular Weight | 484.0 |
| CAS Numbers | 827022-32-2 |
| Storage Condition | 0°C (short term), -20°C (long term), desiccated |
| Solubility | DMSO |
| Purity | 98% by HPLC |
References PubMed ID：:http://www.ncbi.nlm.nih.gov/pubmed/18536095