Mon. Mar 4th, 2024

PD0332991 (Palbociclib) HCl


An orally active, selective inhibitor of the cyclin D kinases Cdk4 (IC50 = 11 nM) and Cdk6 (IC50= 16 nM) with no activity against a panel of 36 additional protein kinases

CAS No:827022-32-2

Chemical Name: 6-​acetyl-​8-​cyclopentyl-​5-​methyl-​2-​[[5-​(1-​piperazinyl)​-​2-​pyridinyl]​amino]​-pyrido[2,​3-​d]​pyrimidin-​7(8H)​-​one, monohydrochloride


Molecular Formula C24H29N7O2 • HCl
Molecular Weight 484.0
CAS Numbers 827022-32-2
Storage Condition 0°C (short term), -20°C (long term), desiccated
Solubility DMSO
Purity 98% by HPLC

References PubMed ID::

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