BIM-46187
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pan G protein inhibitor, specifically silencing Gαq proteins by “freezing” Gαq in its empty pocket conformation, a conformational intermediate along the Gα activation pathway
CAS No: 892546-37-1
Chemical Name: PH-064; (8S,8S)-7,7-[Dithiobis[(2R)-2-amino-1-oxo-3,1-propanediyl]]bis[8-(cyclohexylmethyl)-5,6,7,8-tetrahydro-2-phenyl-imidazo[1,2-a]pyrazine
| Molecular Formula | C44H58N8O2S2 |
| Molecular Weight | 759.11 |
| CAS Numbers | 892546-37-1 |
| Storage Condition | 0°C (short term), -20°C (long term), desiccated |
| Solubility | DMSO |
| Purity | 98% by HPLC |
References PubMed ID：:http://www.ncbi.nlm.nih.gov/pubmed/18508119