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Novel inhibitor of deregulated NRF2 transcriptional activity in cancer, broadly decreasing the expression of NRF2 controlled genes, sensitizing A549 cells to various chemotherapeutic agents, and inhibiting the growth of A549 cells in vitro and in vivo.
CAS No: 1030123-90-0
Chemical Name: N-(1,3-Benzodioxol-5-ylmethyl)-5-(4-fluorophenyl)-thieno[2,3-d]pyrimidin-4-amine
| Molecular Formula | C20H14FN3O2S |
| Molecular Weight | 379.41 |
| CAS Numbers | 1030123-90-0 |
| Storage Condition | 0°C (short term), -20°C (long term), desiccated |
| Solubility | DMSO |
| Purity | 98% by HPLC |
References PubMed ID：:http://www.ncbi.nlm.nih.gov/pubmed/18502832