Sat. May 3rd, 2025

AMG-458

Product Name : AMG-458Description:AMG 458 is a potent c-Met inhibitor with Ki of 1.2 nM, ~350-fold selectivity for c-Met than VEGFR2 in cells.CAS: 913376-83-7Molecular Weight:539.58Formula: C30H29N5O5Chemical Name: 1-(2-hydroxy-2-methylpropyl)-N-5-pyridin-2-yl-5-methyl-3-oxo-2-phenyl-2,3-dihydro-1H-pyrazole-4-carboxamideSmiles : CC1=C(C(=O)N(C2C=CC=CC=2)N1CC(C)(C)O)C(=O)NC1C=CC(=CN=1)OC1C=CN=C2C=C(C=CC2=1)OCInChiKey:…