BMS-202Band: www.medchemexpress.comNovel inhibitor of the PD-1/PD-L1 interaction by inducing PD-L1 dimerization through PD-1 interacting surface CAS No: 1675203-84-5 Chemical Name: N-(2-{-amino}-ethyl)-acetamide TAK-242 Molecular Formula C₂₅H₂₉N₃O₃ Molecular Weight 419.52 CAS Numbers 1675203-84-5…
Shield-1Band: www.medchemexpress.comNovel cell permeable small molecule redulator of specific protein functions The Shield-1 ligand can simultaneously stabilizes and destabilizes a protein of interest depending on the amount of the ligand used within…
SAFit2Band: www.medchemexpress.comHighly selective inhibitor of the FK506-binding protein 51 (FKBP51)CAS No: 1643125-33-0 Chemical Name: (S)-((R)-3-(3,4-Dimethoxyphenyl)-1-(3-(2-morpholinoethoxy)phenyl)propyl) 1-((S)-2-cyclohexyl-2-(3,4,5-trimethoxyphenyl)acetyl)piperidine-2-carboxylate LY2835219 Molecular Formula C46H62N2O10 Molecular Weight 802.99 CAS Numbers 1643125-33-0 Storage Condition 0°C (short term),…
SAFit1Band: www.medchemexpress.comHighly selective inhibitor of the FK506-binding protein 51 (FKBP51) Monomethyl auristatin E Molecular Formula C42H53NO11 Molecular Weight 747.87 CAS Numbers 1643125-32-9 Storage Condition 0°C (short term), -20°C (long…
AZD7762Band: www.medchemexpress.comA potent ATP-competitive checkpoint kinase inhibitorCAS No:860352-01-8 EPZ015666 Molecular Formula C17H19FN4O2S •HCl •H2O Molecular Weight 416.9 CAS Numbers 860352-01-8 Storage Condition 0°C (short term), -20°C (long term), desiccated Solubility…
AZD5363Band: www.medchemexpress.comAn orally bioavailable, selective and potent inhibitor of all PKB/AKT iso-formsCAS No:1143532-39-1 PKC412 Molecular Formula C19H21ClN6O2 Molecular Weight 428.92 CAS Numbers 1143532-39-1 Storage Condition 0°C (short term), -20°C (long…
Aqua-Shield-1Band: www.medchemexpress.comNovel cell permeable small molecule redulator of specific protein functions The Shield-1 ligand can simultaneously stabilizes and destabilizes a protein of interest depending on the amount of the ligand used within…
n a manner related with LDH release and caspase-3 activation after infection. Similarly, Cif homologue in P. luminescens 1655472 triggers apoptosis in insect cells, albeit this activity is not linked…
repressor Numb, the NHLdomain protein Brain tumor, along with the homeodomein transcription element Prospero . In numb, brat, or pros mutants, 1516647 impaired cell fate determination in larval NBs leads…
and, it can not be excluded that the interactions observed in these studies may simply reflect the less efficient binding of liprin-a1 to what we have defined as the inactive…