ML137Band: www.medchemexpress.comHighly selective M1 positive allosteric modulator (PAM)CAS No: 1222834-53-8 Chemical Name: 1-methyl]indole-2,3-dione; ML-137; CID-44251556; VU0366369 BLZ948 Molecular Formula C19H14FN3O2 Molecular Weight 335.33 CAS Numbers 1222834-53-8 References PubMed ID：:http://www.ncbi.nlm.nih.gov/pubmed/18509662
KIN59Band: www.medchemexpress.comAntiangiogenic multitarget antagonist and allosteric inhibitor of the angiogenic enzymeCAS No: 4152-77-6 Chemical Name: 5-O-Tritylinosine; (2R,3R,4S,5R)-9-(3,4-Dihydroxy-5-trityloxymethyl-tetrahydrofuran-2-yl)-1,9- dihydropurin-6-one Siponimod Molecular Formula C29H26N4O5 Molecular Weight 510.54 CAS Numbers 4152-77-6 Storage Condition 0°C…
GSK2830371Band: www.medchemexpress.comThe first orally active, allosteric inhibitor of Wip1 phosphatase through flap-subdomain interactionCAS No: 1404456-53-6 Chemical Name: (S)-5-(((5-Chloro-2-methylpyridin-3-yl)amino)methyl)-N-(3-cyclopentyl-1-(cyclopropylamino)-1-oxopropan-2-yl)thiophene-2-carboxamide AZD-9294 Molecular Formula C23H29ClN4O2S Molecular Weight 461.02 CAS Numbers 1404456-53-6 References PubMed ID：:http://www.ncbi.nlm.nih.gov/pubmed/18509642
FzM1Band: www.medchemexpress.comThe first allosteric ligand of Frizzled4, a member of the Fzd family of Wnt receptors, specifically signaling downstream of Wnt5a to promote dendrite branching and growthCAS No : 1680196-54-6…
FG7142 (ZK-31906)Band: www.medchemexpress.comPartial inverse agonist at the benzodiazepine allosteric site of the GABAA receptor MLN4927 Molecular Formula C13H11N3O Molecular Weight 225.25 CAS Numbers 78538-74-6 Storage Condition 0°C (short term), -20°C…
CYM2503Band: www.medchemexpress.comGalR2-positive allosteric modulatorCAS No: 1308833-36-4 Chemical Name: (9H-fluoren-9-yl)methyl((S)-1(((S)-6(tert-butoxycarbonyl)amino-1-((4-methyl-2-oxo-1,2-dihydroquinolin-7-yl)amino)-1-oxohexan-2-yl)amino])-3-cyclohexyl-1-oxopropan-2-yl)carbamate VX-768 Molecular Formula C44H53N5O7 Molecular Weight 763.92 CAS Numbers 1308833-36-4 Storage Condition 0°C (short term), -20°C (long term), desiccated Solubility DMSO…
VX770Band: www.medchemexpress.comA potentiator of CFTR targeting G551D-CFTR and F508del-CFTR CAS No:873054-44-5 AMG 235 Molecular Formula C24H28N2O3 Molecular Weight 392.49 CAS Numbers 873054-44-5 Storage Condition 0°C (short term), -20°C (long term), desiccated Solubility DMSO 78…
ZLN024Band: www.medchemexpress.comNovel AMPK activator, allosterically stimulating active AMPK heterotrimers CAS No: 723249-01-2 Chemical Name: 2-thio]-pyrimidine Reparixin Molecular Formula C13H13BrN2OS Molecular Weight 325.22 CAS Numbers 723249-01-2 References PubMed ID：:http://www.ncbi.nlm.nih.gov/pubmed/18509461/
Xylopropamine HydrobromideBand: www.medchemexpress.comAnti-inflammatory and analgesic agentCAS No:861007-60-5 Chemical Name: 1-(3,4-Dimethylphenyl)propan-2-amine hydrobromide LY2109764 Molecular Formula C11H18BrN Molecular Weight 244.17 CAS Numbers 861007-60-5 Storage Condition 0°C (short term), -20°C (long term), desiccated Solubility…
WS3Band: www.medchemexpress.comNovel mediator of proliferation of primary retinal pigment epithelial cellsCAS No: 1421227-52-2 Chemical Name: N--3-(trifluoromethyl)phenyl]-amino]carbonyl]amino]phenoxy]-4-pyrimidinyl]-cyclopropanecarboxamide Pexidartinib Molecular Formula C28H30F3N7O3 Molecular Weight 569.58 CAS Numbers 1421227-52-2 References PubMed ID：:http://www.ncbi.nlm.nih.gov/pubmed/18509338