Tue. Jul 8th, 2025

GSK1120212

Band: www.medchemexpress.com

A potent, highly selective and orally active inhibitor of MEK 1 and 2 inhibitor

References:

1: Gilmartin AG, Bleam MR, Groy A, Moss KG, et al., GSK1120212 (JTP-74057) is an inhibitor of MEK activity and activation with favorable pharmacokinetic properties for sustained in vivo pathway inhibition, Clin Cancer Res. 2011 Jan 18. [Epub ahead of print]

CAS No:871700-17-3

Chemical Name: Trametinib, JTP-74057 

Teprenone

Molecular Formula C26H23FIN5O4
Molecular Weight 615.39
CAS Numbers 871700-17-3
Storage Condition 0°C (short term), -20°C (long term), desiccated
Solubility DMSO
Purity 99% (HPLC)

References PubMed ID::http://www.ncbi.nlm.nih.gov/pubmed/18528753

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