Umns (Expedite) 15 ole columns (Expedite) 3′-Fluorescein-dT CPG 1 ole columns (ABI) 0.2 ole columns (ABI) 10 ole column (ABI) 1 ole columns (Expedite) 0.2 ole columns (Expedite) 15 ole columns (Expedite) 20-2961-01 20-2961-10 20-2961-41 20-2961-42 20-2961-13 20-2961-41E 20-2961-42E 20-2961-14 20-2056-01 20-2056-10 20-2056-41 20-2056-42 20-2056-13 20-2056-41E 20-2056-42E 20-2056-14
PAGE NUMBER
1 1
(Continued from Front Page)
RNAs is generated and analyzed. By using -thiotriphosphate nucleotide a a o s t es t sa f c e b t e nlg, h ie fetd y h s b t t t o ,e h b t n e t e i h b t o usiuin xiiig ihr niiin or enhancement of activity, are determined without anything more esoteric than a sequencing gel. At present, NAIM has been used to refine t es r c u a b s sf rt ea t v t o h tutrl ai o h ciiy f Tetrahymena group I intron12, 13, 14, but may be readily extended in any system where a selection process between the a t v a di a t v s e i si p s i l cie n ncie pce s osbe i c u i gc t l s s p o e no l g n nldn aayi, rti r iad interactions, and folding for RNA and even DNA molecules.
Rfrne: eeecs
1. Glen Research Report, 1991, 4, 1-4. 2. F. Wincott, et al., Nucleic Acids Res.,
1995, 23, 2677-2684. 3. B. Sproat, et al., Nucleosides and Nucleotides, 1995, 14, 255-273. 4. M.P. Reddy, N.B. Hanna, and F. Farooqui, Nucleosides and Nucleotides, 1997, 16, 1589-1598. 5. D. Gasparutto, et al., Nucleic Acids Res., 1992, 20, 5159-5166. 6. S.A. Scaringe, F.E. Wincott, and M.H. Caruthers, J Am Chem Soc, 1998, 120, 11820-11821. 7. X. Wu and S. Pitsch, Nucleic Acids Res., 1998, 26, 4315-23. 8. S.A. Strobel and K. Shetty, Proc Natl Acad Sci U S A, 1997, 94, 2903-8. 9. W.A. Pieken, D.B. Olsen, F. Benseler, H. Aurup, and F. Eckstein, Science, 1991, 253, 314-7. 10. A.M. Pyle and T.R. Cech, Nature, 1991, 350, 628-31. 11. M.J. Moore and P.A. Sharp, Science, 1992, 256, 992-7. 12. S. Basu, et al., Nat Struct Biol, 1998, 5, 986-92.
13. S.A. Strobel, L. Ortoleva-Donnelly, S.P. Ryder, J.H. Cate, and E. Moncoeur, Nat Struct Biol, 1998, 5, 60-6. 14. L. Ortoleva-Donnelly, A.A. Szewczak, R.R. Gutell, and S.A. Strobel, RNA, 1998, 4, 498-519.
GLEN RESEARCH ON THE WORLD WIDE WEB Visit Glen Research at http://glenres. Find what’s new, obtain catalog numbers, and access technical support information.
OLIGONUCLEOTIDE DENDRIMERS: FROM POLYLABELLED DNA PROBES TO STABLE NANO-STRUCTURES
M.S. Shchepinov Dept. Of Biochemistry University of Oxford (3)7. These phosphoramidite products permit the synthesis of a dendrimeric structure on top of a conventional “monomeric” oligonucleotide, as well as directly on the solid support. The monomeric and the dendrimeric sequence segments can be prepared with different lengths and different orientation by using 3′- and 5’nucleoside phosphoramidites.989-51-5 SMILES The branches can terminate in any moiety available from the arsenal of phosphoramidite synthons.405911-17-3 Molecular Weight In this way using current synthesis technology, the symmetric doubler and trebler can be easily exploited to develop molecules like the symmetrical examples shown in Scheme 2, with a variety of desirable features.PMID:29083788 Previously, an asymmetric branching reagent6 has been used to prepare comb structures which offer good control of the number and spacing of hybridization sites. Novel applications for dendrimers could also be opened up if mixed terminal functionalities (e.g., oligonucleotides, reporter groups) were introduced onto the outer surface of dendrimers to give asymmetric structures like the example shown in the lower r.MedChemExpress (MCE) offers a wide range of high-quality research chemicals and biochemicals (novel life-science reagents, reference compounds and natural compounds) for scientific use. We have professionally experienced and friendly staff to meet your needs. We are a competent and trustworthy partner for your research and scientific projects.Related websites: https://www.medchemexpress.com