GRN-529Band: www.medchemexpress.comSelective negative allosteric modulator of the mGluR5 receptorCAS No: 1253291-12-1 Chemical Name: (4-Difluoromethoxy-3-pyridin-2-ylethynyl-phenyl)-(5,7-dihydro-pyrrolopyridin-6-yl)-methanone BI-D1870 Molecular Formula C22H15F2N3O2 Molecular Weight 391.37 CAS Numbers 1253291-12-1 References PubMed ID：:http://www.ncbi.nlm.nih.gov/pubmed/18490585
CYM-5520Band: www.medchemexpress.comNovel allosteric agonist of Sphingosine 1-phosphate receptor 2 (S1PR2)CAS No: 1449747-00-5 Chemical Name: 1--6-oxo-1,6-dihydro-pyridine-3-carbonitrile AZD4547 Molecular Formula C21H19N3O2 Molecular Weight 345.39 CAS Numbers 1449747-00-5 References PubMed ID：:http://www.ncbi.nlm.nih.gov/pubmed/18490573
CPI-613Band: www.medchemexpress.comAn E1α pyruvate dehydrogenase (PDH) modulator that prevents cancer cells from metabolizing glucose for energy. CPI-613 has been granted orphan drug status by the US FDA for pancreatic cancerCAS…
CLP-290Band: www.medchemexpress.comNovel KCC2 modulator and prodrug of CLP-257, highly selective for KCC2 over related Cl- transportersCAS No: 1181083-81-7 Chemical Name: phenyl] pyrrolidine-1-carboxylate GDC-0032 Molecular Formula C19H21FN4O3S Molecular Weight 404.46 CAS Numbers…
CaCC(inh)-A01Band: www.medchemexpress.comPotent, selective class A inhibitor of calcium-activated chloride channels CAS No: 407587-33-1 Chemical Name: CaCCinh-A01; 6-t-Butyl-2-(furan-2-carboxamido)-4,5,6,7-tetrahydrobenzo thiophene-3-carboxylic Preladenant Molecular Formula C18H21NO4S Molecular Weight 347.43 CAS Numbers 407587-33-1 Storage Condition 0°C (short…
B355252Band: www.medchemexpress.comNovel potentiator of nerve growth factor (NGF)-induced neurite outgrowth, blocking Ca2+ and ROS production, suppressing glutamate-evoked oxidative stress, and altering the phosphorylation states of Erk kinasesCAS No: 1261576-81-1 Chemical Name: 4-Chloro-N-(naphthalen-1-ylmethyl)-5-(3-(piperazin-1-yl)phenoxy)thiophene-2-sulfonamide…
DefactinibBand: www.medchemexpress.comA non-receptor tyrosine kinaseCAS No:1073154-85-4 Chemical Name: VS-6063, PF-04554878 Acalabrutinib Molecular Formula C20H21F3N8O3S Molecular Weight 510.5 CAS Numbers 1073154-85-4 Storage Condition 0°C (short term), -20°C (long term), desiccated Solubility DMSO…
BMS-599626Band: www.medchemexpress.comAn orally bioavailable pan-HER tyrosine kinase inhibitor. It inhibits human epidermal growth factor receptorsCAS No:8173837-23-1 Chemical Name:AC480 Quisinostat Molecular Formula C27H27FN8O3 Molecular Weight 530.55 CAS Numbers 8173837-23-1 Storage Condition…
AZD9291Band: www.medchemexpress.comAn oral, irreversible, potent and selective third generation tyrosine kinase inhibitor (TKI)CAS No:1421373-65-0 Chemical Name: N-(2-((2-(dimethylamino)ethyl)(methyl)amino)-4-methoxy-5-((4-(1-methyl-1H-indol-3-yl)pyrimidin-2-yl)amino)phenyl)acrylamide CH5424802 Molecular Formula C28H33N7O2 Molecular Weight 499.6 CAS Numbers 1421373-65-0 Storage Condition 0°C (short…
AZD4547Band: www.medchemexpress.comA potent, selective and orally active pan-FGFR inhibitorCAS No:1035270-39-3 Selumetinib Molecular Formula C26H33N5O3 Molecular Weight 463.58 CAS Numbers 1035270-39-3 Storage Condition 0°C (short term), -20°C (long term), desiccated Solubility…