XL-139 (BMS-833923)Band: www.medchemexpress.comAn orally bioavailable small-molecule inhibitor of Smoothened with potential antineoplastic activity; inhibits BODIPY cyclopamine binding to SMO in a dose-dependent manner with an IC50 of 21 nM.CAS No:1059734-66-5…
AMG-925Band: www.medchemexpress.comPotent, selective, and orally available FLT3/CDK4 dual inhibitorCAS No:1401033-86-0 Vatalanib Molecular Formula C26H29N7O2 Molecular Weight 471.6 CAS Numbers 1401033-86-0 Storage Condition 0°C (short term), -20°C (long term), desiccated Solubility…
AMG-458Band: www.medchemexpress.comA potent inhibitor of c-Met with an IC50 of 60 nMCAS No:913376-83-7 Necrosulfonamide Molecular Formula C30H29N5O5 Molecular Weight 539.58 CAS Numbers 913376-83-7 Storage Condition 0°C (short term), -20°C (long…
AMG-232Band: www.medchemexpress.comAn extremely potent MDM2 inhibitorCAS No:1352066-68-2 Tonabersat Molecular Formula C28H35Cl2NO5S Molecular Weight 568.6 CAS Numbers 1352066-68-2 Storage Condition 0°C (short term), -20°C (long term), desiccated Solubility DMSO or Ethanol…
AMG-1Band: www.medchemexpress.comA potent inhibitor of human c-Met and RONCAS No:913376-84-8 1-NM-PP3 Molecular Formula C31H29FN4O5 Molecular Weight 556.58 CAS Numbers 913376-84-8 Storage Condition 0°C (short term), -20°C (long term), desiccated Solubility…
AM374Band: www.medchemexpress.comPotent in vitro and in vivo inhibitor of fatty acid amide hydrolase (FAAH) CAS No: 86855-26-7 Chemical Name: HDSF; Hexadecyl sulfonylfluoride CX-5463 Molecular Formula C16H33FO2S Molecular Weight 308.5 CAS Numbers…
AI-4-57 HydrochlorideBand: www.medchemexpress.comLigand to the CBFß portion of the CBFß-SMMHC fusion protein, inhibiting its binding to the Runt domain of RUNX proteins, also being a modest potency inhibitor of the…
AGK-2Band: www.medchemexpress.comPotent and selective inhibitor of sirtuin 2 (SIRT2) CAS No: 304896-28-4 Chemical Name: 2-Cyano-3--N-5-quinolinyl-2-propenamide Erdafitinib Molecular Formula C23H13Cl2N3O2 Molecular Weight 434.3 CAS Numbers 304896-28-4 Storage Condition 0°C (short term), -20°C…
Afatinib DimaleateBand: www.medchemexpress.comAn irreversible EGFR/HER2 inhibitor with an IC50 of 14 nM for in vitro potency against HER2CAS No:850140-73-7 Alternative Name: BIBW2992 Dimaleate AdipoRon Molecular Formula C24H25ClFN5O3·2C4H4O4 Molecular Weight 718.08 CAS…
AbacavirBand: www.medchemexpress.comReverse transcriptase inhibitor (NRTI) CAS No: 136470-78-5 Chemical Name: {(1S,4R)-4-cyclopent-2-en-1-yl}methanol GDC-0855 Molecular Formula C14H18N6O•HCl Molecular Weight 322.80 CAS Numbers 136470-78-5 Storage Condition 0°C (short term), -20°C (long term), desiccated Solubility…