Fri. Jul 4th, 2025

XL-139 (BMS-833923)

Band: www.medchemexpress.com

An orally bioavailable small-molecule inhibitor of Smoothened with potential antineoplastic activity; inhibits BODIPY cyclopamine binding to SMO in a dose-dependent manner with an IC50 of 21 nM.

CAS No:1059734-66-5

5-Deazaneplanocin A (hydrochloride)

Molecular Formula C30H27N5O
Molecular Weight 473.57
CAS Numbers 1059734-66-5
Storage Condition 0°C (short term), -20°C (long term), desiccated
Solubility DMSO
Purity 98% by HPLC

References PubMed ID::http://www.ncbi.nlm.nih.gov/pubmed/18505435

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