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Potent and selective inhibitor of Brutons tyrosine kinase (BTK). Inhibits recombinant BTK with an IC50value of 2.5 μM and has no activity on other protein kinases ( including JAK1, JAK3, HCK, EGFR kinase and insulin receptor kinase) at concentrations of up to 278 μM.
CAS No:244240-24-2
Chemical Name: 2-Cyano-N-(2,5-dibromophenyl)-3-hyd
| Molecular Formula | C11H8Br2N2O2 |
| Molecular Weight | 360 |
| CAS Numbers | 244240-24-2 |
| Storage Condition | 0°C (short term), -20°C (long term), desiccated |
| Solubility | DMSO |
| Purity | 98% by HPLC |
References PubMed ID：:http://www.ncbi.nlm.nih.gov/pubmed/18534229