Tue. Jul 8th, 2025

GNE-7915

Band: www.medchemexpress.com

A Blood-Brain Barrier (BBB) penetrable small molecule inhibitor of Leucine-Rich Repeat Kinase 2 (LRRK2)

References:

1. A.A. Estrada, et al., Discovery of Highly Potent, Selective, and Brain-Penetrable Leucine-Rich Repeat Kinase 2 (LRRK2) Small Molecule Inhibitors, J. Med. Chem., 2012, 55 (22), pp 9416–9433
2. M.E. Kavanagh, et al, Bio.& Med. Chem Letters, 2013, 23 (13) Pages 3690–3696

CAS No:1351761-44-8

TRO 19627

Molecular Formula C19H21F4N5O3
Molecular Weight 443.4
CAS Numbers 1351761-44-8
Storage Condition 0°C (short term), -20°C (long term), desiccated
Solubility DMSO
Purity 99% (HPLC)

References PubMed ID::http://www.ncbi.nlm.nih.gov/pubmed/18528423

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