**Background** Alzheimer’s disease is a progressive neurodegenerative disorder characterized by the accumulation of amyloid-beta (Aβ) plaques in the brain. A key step in the production of these plaques is the…
**Background** Colorectal cancer remains a significant global health challenge, characterized by complex interactions between tumor cells and the immune microenvironment. A critical component of immune regulation is the T-cell receptor…
**Background** Progestins are synthetic versions of progesterone used extensively in oral contraception and hormone replacement therapy. These compounds play a critical role in regulating the menstrual cycle and managing various…
**Background** Muscarinic cholinergic receptors (mAChRs) are G protein-coupled receptors that play a critical role in regulating various physiological processes across the central and peripheral nervous systems. Among these, the M1…
The competitive adsorption behavior of mixed dye systems—specifically methyl orange (MO), indigo carmine (IC), and methylene blue (MB)—on polystyrene-based adsorbents reveals complex intermolecular interactions that govern selectivity, capacity, and process…
The interaction between 5-methoxy-2-mercaptobenzimidazole (5-M-2-MB) and tyrosinase was investigated through a multidisciplinary approach combining enzyme kinetics, fluorescence spectroscopy, thermodynamic analysis, energy transfer studies, and molecular docking. The results demonstrate that…
The manipulation of spin-crossover (SCO) behavior in molecular materials is fundamentally tied to the spatial organization and intermolecular interactions within the solid state. This study presents a comprehensive investigation into…
Large (mega) Stokes shift molecules have emerged as transformative tools in bioimaging and sensing due to their ability to minimize self-absorption, reduce background noise, and enable multiplexed detection. This review…
The escalating threat of healthcare-associated infections demands innovative materials capable of long-term microbial resistance. This study presents a rational design strategy for high-performance antimicrobial cotton textiles through the synergistic integration…
Hypomethylating agents (HMAs), including azacitidine and decitabine, have been a cornerstone of treatment for elderly or unfit patients with acute myeloid leukemia (AML) and myelodysplastic syndromes (MDS) for decades. These…