Name :
MUC-1 (Human) Recombinant Protein
Biological Activity :
Human MUC-1 (NP_001018016.1, 1 a.a. – 167 a.a.) partial recombinant protein with Fc and His tag at C-terminus expressed in HEK293 cells.Bioactive Protein,Bioactive Proteins,Bioactive,Active,Functional Protein,Functional Proteins,Recombinant Human Protein,Recombinant Human Proteins,Human Recombinant Protein,Human Recombinant Proteins,HuPro
Tag :
Result of activity analysis
Protein Accession No. :
P15941
Protein Accession No.URL :
https://www.ncbi.nlm.nih.gov/gene?cmd=Retrieve&dopt=Graphics&list_uids=4582
Amino Acid Sequence :
Molecular Weight :
60-75
Storage and Stability :
Store the lyophilized protein at -20°C to -80°C for long term.After reconstitution to a concentration of 0.1-0.5 mg/mL in sterile distilled water, the protein solution is stable at -20°C for 3 months, at 2-8°C for up to 1 week.Aliquot to avoid repeated freezing and thawing.
Host :
Human
Interspecies Antigen Sequence :
Preparation Method :
Mammalian cell (HEK293) expression system
Purification :
Ni-sepharose purification
Quality Control Testing :
SDS-PAGE Stained with Coomassie Blue MUC-1 (Human) Recombinant Protein (Cat #P6772) was determined by SDS-PAGE with Coomassie Blue, showing a band at 60-75 kDa.
Storage Buffer :
Lyophilized from PBS, pH 7.4.
Applications :
SDS-PAGE，
Gene Name :
MUC1
Gene Alias :
CD227, EMA, H23AG, MAM6, PEM, PEMT, PUM
Gene Description :
mucin 1, cell surface associated
Gene Summary :
This gene is a member of the mucin family and encodes a membrane bound, glycosylated phosphoprotein. The protein is anchored to the apical surface of many epithelia by a transmembrane domain, with the degree of glycosylation varying with cell type. It also includes a 20 aa variable number tandem repeat (VNTR) domain, with the number of repeats varying from 20 to 120 in different individuals. The protein serves a protective function by binding to pathogens and also functions in a cell signaling capacity. Overexpression, aberrant intracellular localization, and changes in glycosylation of this protein have been associated with carcinomas. Multiple alternatively spliced transcript variants that encode different isoforms of this gene have been reported, but the full-length nature of only some has been determined. [provided by RefSeq
Other Designations :
DF3 antigen|H23 antigen|MUC-1/SEC|MUC-1/X|MUC1/ZD|OTTHUMP00000033787|OTTHUMP00000033790|OTTHUMP00000033795|breast carcinoma-associated antigen DF3|episialin|mucin 1|mucin 1, transmembrane|peanut-reactive urinary mucin|polymorphic epithelial mucin|tumor as
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