Product Name :
SARS-CoV-2 Spike RBD (Omicron BQ.1.1) Protein 2631
express system :
HEK293
Product tag :
C-His
Purity:
> 95% as determined by Tris-Bis PAGE;> 95% as determined by HPLC
Background:
The ongoing coronavirus disease 2019 (COVID-19) pandemic has prioritized the development of small-animal models for severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). The resulting mouse-adapted strain at passage 6 (called MASCp6) showed increased infectivity in mouse lung and led to interstitial pneumonia and inflammatory responses in both young and aged mice after intranasal inoculation. Deep sequencing revealed a panel of adaptive mutations potentially associated with the increased virulence. In particular, the N501Y mutation is located at the receptor binding domain (RBD) of the spike protein.
Molecular Weight:
The protein has a predicted MW of 25.98 kDa. Due to glycosylation, the protein migrates to 35-43 kDa based on Tris-Bis PAGE result.
Available Size :
100 µg, 500 µg
Endotoxin:
Less than 1EU per μg by the LAL method.
Form :
Lyophilized
Storage Instructions :
Valid for 12 months from date of receipt when stored at -80°C. Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
Storage buffer:
Shipped at ambient temperature.
Additional Information:
inaccessionQHD43416|express systemHEK293|product tagC-His|purity> 95% as determined by Tris-Bis PAGE;> 95% as determined by HPLC|backgroundThe ongoing coronavirus disease 2019 (COVID-19) pandemic has prioritized the development of small-animal models for severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). The resulting mouse-adapted strain at passage 6 (called MASCp6) showed increased infectivity in mouse lung and led to interstitial pneumonia and inflammatory responses in both young and aged mice after intranasal inoculation. Deep sequencing revealed a panel of adaptive mutations potentially associated with the increased virulence. In particular, the N501Y mutation is located at the receptor binding domain (RBD) of the spike protein.|molecular weightThe protein has a predicted MW of 25.98 kDa. Due to glycosylation, the protein migrates to 35-43 kDa based on Tris-Bis PAGE result.|available size100 g, 500 g|endotoxinLess than 1EU per g by the LAL method.|SARS-CoV-2 Spike RBD (Omicron BQ.1.1) Protein 2631proteinSize and concentration100, 500g and lyophilizedFormLyophilizedStorage InstructionsValid for 12 months from date of receipt when stored at -80C. Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.Storage bufferShipped at ambient temperature.Purity> 95% as determined by Tris-Bis PAGEtarget relevanceNo information|
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