Name :
Human GFRAL Protein, His Tag
Uniprot ID :
Q6UXV0
Common Name :
Synonyms :
bA360D14.1;C6orf144;GRAL;UNQ9356
Application :
Recommended Dilutions :
Formulation &Reconstitution :
Lyophilized from sterile PBS, pH 7.4. Normally 5 % – 8% trehalose is added as protectants before lyophilization. Please see Certificate of Analysis for specific instructions of reconstitution.
Host Species :
IgG type :
Reactivity :
Target :
GFRAL
Description :
Recombinant human GFRAL protein with C-terminal 6×His tag
Delivery :
In Stock
Storage&Shipping :
Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
Background :
Brainstem-restricted receptor for GDF15 which regulates food intake, energy expenditure and body weight in response to metabolic and toxin-induced stresses (PubMed:28953886, PubMed:28846097, PubMed:28846098, PubMed:28846099). Upon interaction with its ligand, GDF15, interacts with RET and induces cellular signaling through activation of MAPK- and AKT- signaling pathways.[UniProtKB/Swiss-Prot Function]
Usage :
Research use only
Related websites: https://www.medchemexpress.com/antibodies.html
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